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Allele : Slc25a46<em2Jvt> solute carrier family 25, member 46; endonuclease-mediated mutation 2, JL Vilotte

Primary Identifier  MGI:6358092 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Slc25a46
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  TALEN genome editing technology was used to generate a 15 bp insertion / 3 bp deletion, causing replacement of 2 amino acids in the encoded protein from the first transmembrane domain by six modified amino-acids. However, no detectable protein was present in mitochondria derived from mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Tg18,
  • Tg18
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele