Primary Identifier | MGI:1921444 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 74194 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including actin filament organization; cell migration; and regulation of actin cytoskeleton organization. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in cytosol and plasma membrane. Is expressed in central nervous system; genitourinary system; retina; and vascular system. Orthologous to human RND3 (Rho family GTPase 3). PHENOTYPE: Mice homozygous for a mutation in this gene display premature death with postnatal growth retardation and wasting, delayed development, absence of the common peroneal nerve and impaired motor capabilities. [provided by MGI curators] |