| Primary Identifier | MGI:2685974 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 382113 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables riboflavin transmembrane transporter activity. Acts upstream of or within flagellated sperm motility and sperm capacitation. Located in sperm principal piece. Is active in mitochondrial inner membrane. Orthologous to human SLC22A14 (solute carrier family 22 member 14). PHENOTYPE: Mice homozygous for a null allele show severe male infertility, asthenozoospermia, impaired sperm capacitation with intracellular pH dysregulation, decreased in vitro fertilization, abnormal sperm flagellar bending caused by osmotic cell swelling, and structural defects in the annulus. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
