Primary Identifier | MGI:5570746 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inducible, Inserted expressed sequence, Reporter | Gene | Tg(tetO-MYCN,-luc)#Waw |
Strain of Origin | Not Specified | Induced With | doxycycline/tetracycline |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The bi-directional tetracycline-responsive operator drives inducible expression of the human MYCN cDNA and firefly luciferase. In double transgenic mice also expressing the tetracycline transactivating or reverse transactivating element (tTA or rtTA), expression of MYCN can be regulated by doxycycline administration or removal. |