| Type | MGI:General | Description | when mated with wild-type males of proven fertility, females produce fewer pups than controls after their first parity over a 6 mo-period of continuous breeding, females have significantly fewer litters, smaller litter size, and reduced fecundity relative controls during natural mating, time to first litter (as measured by plug date to delivery date) is extended, suggesting that many females fail to get pregnant after their first mating |