Primary Identifier | MGI:5501232 | Allele Type | Targeted |
Attribute String | Not Specified | Gene | Birc2 |
Transmission | Germline | Strain of Origin | 129 x C57BL/6 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting construct was designed to insert a loxP- and frt-flanked neomycin (neo) resistance cassette downstream of exon 7. A point mutation was introduced in exon 7, encoding a RING domain, resulting in an H582A mutation. Cre-mediated recombination removed the neo cassette. |