Primary Identifier | MGI:3809291 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Tmprss6 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A cassette containing a puromycin resistance gene, an Hprt minigene, and an agouti minigene was inserted 3' of exon 6. Following this insert, exons 3-6 were duplicated. Northern blot analysis indicated the complete absensence of mRNA transcribed from this allele in liver RNA. |