| Primary Identifier | MGI:3794857 | Allele Type | Targeted |
| Gene | Pparg | Transmission | Germline |
| Strain of Origin | 129S6/SvEvTac | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 2 was replaced with an exon 2 containing a nucleotide substitution that resulted in the amino acid substitution of alanine for serine at position 112 (S112A). A floxed neo cassette downstream of the modified exon 2 used for selection purposes was removed by cre-mediated recombination in ES cells. This mutant version of PPARgamma is nonphosphorylatable and has more biological activity. |
