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Allele : Kcnma1<tm1Ruth> potassium large conductance calcium-activated channel, subfamily M, alpha member 1; targeted mutation 1, P Ruth

Primary Identifier  MGI:3050114 Allele Type  Targeted
Attribute String  Null/knockout Gene  Kcnma1
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A single loxp site was inserted upstream of the exon encoding the pore-forming alpha subunit, and a floxed neo-TK cassette downstream. Transient cre-expression excised the floxed region including the exon and neo-TK. Southern blot and PCR confirmed recombination and Western blot of brain membrane proteins from mutants indicated absence of the C-terminus of the alpha subunit.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • BKalpha<->,
  • BK<->,
  • BK<->,
  • BKalpha<->,
  • BK-KO,
  • BK L1,
  • BK L1,
  • BK-KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

33 Publication categories

Trail: Allele