Primary Identifier | MGI:4461063 | Allele Type | Targeted |
Gene | G6pc2 | Transmission | Germline |
Strain of Origin | 129S2/SvPas | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 5 was replaced with an frt flanked neo cassette and a modified exon 5 in which nucleotide substitutions result in the amino acid substitutions of alanine for lysine at position 209 (K209A) and alanine for phenylalanine at position 213 (F213A). Flp mediated recombination removed the neo cassette leaving a single frt site downstream of the modified exon 5. The modified residues participate in T cell receptor contact. |