| Primary Identifier | MGI:1352754 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 29876 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable chloride channel activity. Involved in keratinocyte differentiation. Acts upstream of or within several processes, including endothelial cell morphogenesis; vacuolar acidification; and vasculature development. Located in mitochondrion. Is expressed in brain; skin; and spleen. Orthologous to human CLIC4 (chloride intracellular channel 4). PHENOTYPE: Mice homozygous for null mutations may display decreased survival, body weight and female fertility, impaired angiogenesis, increased suscpetibility to Listeria infection, increased resistance to LPS treatment, skin erosions and/or delayed wound healing. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
