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Protein Coding Gene : Bmx BMX non-receptor tyrosine kinase

Primary Identifier  MGI:1101778 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  12169
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in B cell receptor signaling pathway and adaptive immune response. Predicted to act upstream of or within apoptotic process and cell adhesion. Predicted to be located in nucleoplasm and ruffle membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; hemolymphoid system; and mammary gland. Orthologous to human BMX (BMX non-receptor tyrosine kinase).
PHENOTYPE: Mice homozygous for a null mutation are fertile and have a normal life span but are protected from arthritis in a passive transfer model. [provided by MGI curators]
  • synonyms:
  • Tyro8,
  • Etk,
  • MGD-MRK-38318,
  • Etk/Bmx,
  • MGI:109273,
  • TYRO8 protein tyrosine kinase 8,
  • BMX non-receptor tyrosine kinase,
  • Bmx

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

9 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For