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Protein Coding Gene : Krt7 keratin 7
Primary Identifier  MGI:96704 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  110310
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Predicted to be located in cytosol and intermediate filament cytoskeleton. Predicted to be active in keratin filament. Is expressed in several structures, including alimentary system; genitourinary system; sensory organ; skin; and trophectoderm. Orthologous to human KRT7 (keratin 7).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased cell proliferation of urothelial cells without histological evidence of hyperplasia. [provided by MGI curators]
  • synonyms:
  • Krt7,
  • MGD-MRK-11659,
  • K7,
  • DNA segment, Chr 15, Wayne State University 77, expressed,
  • Krt2-7,
  • keratin 7,
  • MGD-MRK-34004,
  • D15Wsu77e,
  • MGI:106312,
  • Cytokeratin 7,
  • keratin complex 2, basic, gene 7
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Features --> Cross References

Genome

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4 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Genes --> Homologs

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3 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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1 Driver For

Trail: ProteinCodingGene




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