Primary Identifier | MGI:1921981 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 382030 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to be involved in positive regulation of protein dephosphorylation; positive regulation of triglyceride biosynthetic process; and protein localization to nucleus. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in cytosol and nuclear membrane. Predicted to be part of Nem1-Spo7 phosphatase complex. Predicted to be active in cytoplasm. Orthologous to human CNEP1R1 (CTD nuclear envelope phosphatase 1 regulatory subunit 1). PHENOTYPE: Conditional knockout in myeloid cells results in reduced levels of pro-inflammatory cytokines and increased susceptibility to L. monocytogenes infection. [provided by MGI curators] |