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Publication : Expression of p53 protein in tissues and organs of human and mouse embryo.

First Author  Lichnovský V Year  1994
Journal  Acta Univ Palacki Olomuc Fac Med Volume  138
Pages  25-7 PubMed ID  8714088
Mgi Jnum  J:36945 Mgi Id  MGI:84358
Citation  Lichnovsky V, et al. (1994) Expression of p53 protein in tissues and organs of human and mouse embryo. Acta Univ Palacki Olomuc Fac Med 138:25-7
abstractText  The expression of p53 was demonstrated in the cells of some tissues in the various stages of human embryo development. The distribution of this protein correlates in some cases with sites of higher proliferative activity as demonstrated by PCNA/cyclin detection. It is necessary to prove whether the p53 protein participates in the regulation of cell division, or it is the aberrant expression of unfunctional p53 which is induced in sites of higher proliferation by feed back regulatory mechanism.
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