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Allele : Tardbp<em9Lutzy> TAR DNA binding protein; endonuclease-mediated mutation 9, Cathy Lutz
Primary Identifier  MGI:6295441 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Tardbp
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 genome editing is used to introduce a G348C amino acid substitution. In humans, the G348C substitution is associated with amyotrophic lateral sclerosis.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Tardbp<G348C>,
  • Tardbp<G348C>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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