| Primary Identifier | MGI:1919231 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 71981 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable several functions, including ATP binding activity; RNA helicase activity; and nucleic acid binding activity. Involved in several processes, including male meiotic nuclear division; piRNA processing; and siRNA-mediated retrotransposon silencing by heterochromatin formation. Part of PET complex. Is expressed in several structures, including central nervous system; genitourinary system; gut; hemolymphoid system gland; and sensory organ. Orthologous to human TDRD12 (tudor domain containing 12). PHENOTYPE: Homozygous males are infertile with small testes. Spermatogenesis is arrested predominantly at the pachytene spermatocyte stage. Retrotransposon hopping is derepressed in germ cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
