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Allele : Themis<m2Btlr> thymocyte selection associated; mutation 2, Bruce Beutler

Primary Identifier  MGI:5806438 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Themis
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU-induced A to G transition at base pair 28,668,727 (v38) on chromosome 10, or base pair 401 in the GenBank genomic region NC_000076. The mutation corresponds to residue 368 in the mRNA sequence NM_178666 within exon 1 of 6 total exons. The mutation results in an isoleucine (I) to asparagine (N) substitution at position 23 (I23N) in the protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • death_valley,
  • death_valley
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele