Primary Identifier | MGI:5806438 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Themis |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced A to G transition at base pair 28,668,727 (v38) on chromosome 10, or base pair 401 in the GenBank genomic region NC_000076. The mutation corresponds to residue 368 in the mRNA sequence NM_178666 within exon 1 of 6 total exons. The mutation results in an isoleucine (I) to asparagine (N) substitution at position 23 (I23N) in the protein. |