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Protein Domain : MID domain of medPIWI

Primary Identifier  IPR041285 Type  Domain
Short Name  MID_MedPIWI
description  MID domain of the medPIWI PIWI/Argonaute module. medPIWI is the core globular domain of the Med13 protein. Med13 is one member of the CDK8 subcomplex of the Mediator transcriptional coactivator complex. The medPIWI module in Med13 is predicted to bind double-stranded nucleic acids, triggering the experimentally-observed conformational switch in the CDK8 subcomplex which regulates the Mediator complex [].

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6 Protein Domain Regions