| Primary Identifier | IPR029820 | Type | Family |
| Short Name | BATF |
| description | Basic leucine zipper transcriptional factor ATF-like (BATF) is a transcription factor that dimerises with Jun class factors to bind AP-1 DNA sites []. It does not only inhibit AP-1-driven transcription, but also has positive transcriptional activities in dendritic cells, B cells and T cells through its interaction with members of the interferon-regulatory factor (IRF) family []. BATF controls the differentiation of lineage-specific cells in the immune system: specifically mediates the differentiation of T-helper 17 cells (Th17), follicular T-helper cells (TfH), CD8+ dendritic cells and class-switch recombination (CSR) in B-cells []. |
