| Primary Identifier | IPR026438 | Type | Family |
| Short Name | GGGP_synthase_archaea |
| description | This enzyme, known also as GGGP synthase and GGGPS, is a prenyltransferase that catalyses the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). It catalyses the stereospecific first step in the biosynthesis of the characteristic membrane diether lipids of archaea. To a much lesser extent, is also able to use heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) as the prenyl donor. Interestingly, the closest homologues outside this family are not the functionally equivalent enzymes of other archaea, but rather functionally distinct bacterial enzymes [, ]. |
