| Primary Identifier | MGI:5635289 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Sesn1 |
| Transmission | Germline | Strain of Origin | C57BL/6N |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | EUCOMM |
| molecularNote | The L1L2_gt0 cassette was inserted at position 41778056 of Chromosome 10 upstream of the critical exon 6 (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site was inserted downstream of the targeted exon 6 at position 41778892. The critical exon 6 were thus flanked by loxP sites and subsequent cre-mediated excision deleted the critical sequence and the neomycin selection cassette yielding this knockout reporter allele. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. |
