| Primary Identifier | MGI:1931086 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 80385 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Acts upstream of or within several processes, including natural killer cell differentiation; neutrophil-mediated killing of gram-negative bacterium; and regulation of cytokine production. Located in mitochondrion. Is expressed in liver and metanephros. Orthologous to human TUSC2 (tumor suppressor 2, mitochondrial calcium regulator). PHENOTYPE: Mice homozygous for a knock-out allele develop signs of autoimmune disease and premature aging and exhibit multiple aging-related pathologies, chronic inflammation, low reserve respiratory capacity, altered steady-state and stimuli-induced calcium homeostasis, and premature death. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
