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Allele : Tg(GFAP-cre/ERT2)1Fki transgene insertion 1, Frank Kirchhoff

Primary Identifier  MGI:4418665 Allele Type  Transgenic
Attribute String  Inducible, Recombinase Gene  Tg(GFAP-cre/ERT2)1Fki
Strain of Origin  FVB/N Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  The construct contains the human glial fibrillary acidic protein (GFAP), a tripartite intron composed of an adenovirus splice donor and immunoglobulin G splice acceptor site, the open reading frame of cre/ERT2 (cre fused to an improved mutant human estrogen receptor), and a human growth hormone polyA site. The linearized 5.3kb fragment was injected into FVB/N fertilized oocytes. Two lines were found to express cre protein and one line designated 1 (called GCTF in J:156009) was analyzed further.
  • mutations:
  • Insertion
  • synonyms:
  • GFAP-CreERT2,
  • TgN(GFAP-CreERT2)GCTF-Fki,
  • GFAP-CreERT2,
  • TgN(GFAP-CreERT2)GCTF-Fki
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

Trail: Allele

42 Publication categories

Trail: Allele