| Primary Identifier | IPR030366 | Type | Family |
| Short Name | ABCA2 |
| description | ATP-binding cassette subfamily A member 2 (ABCA2) belongs to the ABC transporter family, whose remembers are full-length transporters organised in two tandem halves, each with a hydrophobic TMD followed by a cytoplasmic NBD [].ABCA2 is mainly expressed in the central nervous system, ovary and macrophages [, ]. It may modulate cholesterol homeostasis in neuronal cells []. It may regulate esterification of plasma membrane cholesterol by modulation of sphingolipid metabolism []. |
