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Protein Coding Gene : Ccdc3 coiled-coil domain containing 3

Primary Identifier  MGI:1921436 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  74186
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Acts upstream of or within negative regulation of gene expression; positive regulation of fat cell differentiation; and regulation of lipid biosynthetic process. Located in extracellular region. Is expressed in cerebral cortex mantle layer; embryo mesenchyme; floor plate; genitourinary system; and nose. Orthologous to human CCDC3 (coiled-coil domain containing 3).
PHENOTYPE: Aging mice homozygous for a null allele are lean and show decreased epididymal and subcutaneous adipose tissue weight and adipocyte size, mild hyperglycemia, increased insulin sensitivity, reduced liver triglyceride levels and steatosis, and fewer inflammatory cells in epididymal fat tissue. [provided by MGI curators]
  • synonyms:
  • coiled-coil domain containing 3,
  • Ccdc3,
  • 2310045O21Rik,
  • RIKEN cDNA 2310045O21 gene

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

3 Driver For