| First Author | Roskoski R Jr | Year | 2008 |
| Journal | Biochem Biophys Res Commun | Volume | 375 |
| Issue | 3 | Pages | 287-91 |
| PubMed ID | 18680722 | Mgi Jnum | J:140210 |
| Mgi Id | MGI:3812276 | Doi | 10.1016/j.bbrc.2008.07.121 |
| Citation | Roskoski R Jr (2008) VEGF receptor protein-tyrosine kinases: structure and regulation. Biochem Biophys Res Commun 375(3):287-91 |
| abstractText | The human VEGF family consists of VEGF (VEGF-A), VEGF-B, VEGF-C, VEGF-D, and placental growth factor (PlGF). The VEGF family of receptors consists of three protein-tyrosine kinases (VEGFR1, VEGFR2, and VEGFR3) and two non-protein kinase co-receptors (neuropilin-1 and neuropilin-2). These components participate in new blood vessel formation from angioblasts (vasculogenesis) and new blood vessel formation from pre-existing vasculature (angiogenesis). Interaction between VEGFR1 and VEGFR2 or VEGFR2 and VEGFR3 alters receptor tyrosine phosphorylation. |
