Primary Identifier | MGI:6714092 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase | Gene | Tg(Nanog-cre/Esr1*)4470Mms |
Strain of Origin | C57BL/6N | Induced With | tamoxifen |
Is Recombinase | true | Is Wild Type | false |
molecularNote | The bacterial artificial chromosome, RP23-406B15, containing Nanog and its regulatory sequences was modified to insert a cDNA encoding Cre/Esr1* fusion protein into the translation initiation start site. Additional sequencing indicates that the fusion is not ERT2, but appears to be a mutant derivative of the mouse estrogen receptor. |