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Allele : F2<tm1Jes> coagulation factor II; targeted mutation 1, J Evan Sadler

Primary Identifier  MGI:2177949 Allele Type  Targeted
Attribute String  Null/knockout Gene  F2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced a genomic DNA fragment that contains exons 7-11, which encode one of the kringle domains, the activation cleavage site and part of the active site. Western blot analysis on liver extracts derived from homozygous mice confirmed that no detectable protein was expressed from this allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Cf2-,
  • Cf2-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele