| Type | MGI:General | Description | in an initial pipeline study, both sexes show an ~1.5-fold increase in body weight at 16 weeks of age, with a lager effect in female mice in a second, larger cohort study, females gain significantly more weight starting from 5 weeks of age and cumulatively gain 16% more weight by 16 weeks of age, while males gain 11% more weight by week 16 relative to wild-type controls |
