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Allele : Plk4<em5Ahol> polo like kinase 4; endonuclease-mediated mutation 5, Andrew Holland
Primary Identifier  MGI:7341837 Allele Type  Endonuclease-mediated
Attribute String  Conditional ready Gene  Plk4
Strain of Origin  (C57BL/6 x SJL/J)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/cas9 genome editing uses guide RNAs, targeting DNA sequence 5';-aagctaggactttaatactc-3', to insert a loxP flanked STOP cassette into intron 4. Plk4-201 was used as reference for the exon number and the guide sequences.
  • mutations:
  • Insertion
  • synonyms:
  • Plk4<cWT>,
  • Plk4<cWT>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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