|  Help  |  About  |  Contact Us

Protein Domain : Histone H2A deubiquitinase MYSM1

Primary Identifier  IPR033497 Type  Family
Short Name  MYSM1
description  MYSM1 (MEROPS identifier M67.005) is a deubiquitinase specific for monoubiquitinated histone H2A (uH2A). It is a positive regulator of androgen receptor (AR) activity on an AR responsive element (ARE)-containing reporter gene []. It plays important regulator roles in hematopoietic stem cell function, blood cell production and immune response []. It has been shown to represses innate immunity and autoimmunity through suppressing the cGAS-STING Pathway [].

0 Child Features

0 Parent Features

1 Protein Domain Regions