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Allele : Tg(LYZ-rtTA2S*M2,tetO-ELAVL1)632Dkon transgene insertion 632, Dimitris Kontoyiannis

Primary Identifier  MGI:5429340 Allele Type  Transgenic
Attribute String  Inducible, Inserted expressed sequence, Transactivator Gene  Tg(LYZ-rtTA2S*M2,tetO-ELAVL1)632Dkon
Strain of Origin  (CBA x C57BL/6)F2 Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  The first vector contains the human lysozyme promoter driving immune-specific expression of the tet-on effector transgene with the rtTA2S*M2 variant. A second vector contains the tetracycline responsive element driving the inducible expression of the human cDNA with an HA tag. Lines 632 and 662 were generated with five (Tg632) or two (Tg662) copies of the rtTA and comparable (six to eight) copies of the HA-ELAVL1 transgenes.
  • mutations:
  • Insertion
  • synonyms:
  • TgLrTtA-HAHuRL.632,
  • TgLrTtA-HAHuRL.632,
  • Tg632,
  • Tg632,
  • Tg(LYS2-rtTA2S*M2,tetO-ELAVL1)632Dkon,
  • Tg(LYS2-rtTA2S*M2,tetO-ELAVL1)632Dkon
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele