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Protein Coding Gene : Pnlip pancreatic lipase
Primary Identifier  MGI:97722 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  69060
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables triglyceride lipase activity. Acts upstream of or within intestinal cholesterol absorption. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in pons and pons mantle layer. Orthologous to human PNLIP (pancreatic lipase).
PHENOTYPE: Homozygous null mice show impaired dietary cholesterol, triglyceride and retinyl ester absorption, resistance to diet-induced obesity, and insulin resistance. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-13544,
  • MGC:74173,
  • pancreatic triglyceride lipase,
  • PTL,
  • MGI:1916310,
  • RIKEN cDNA 1810007A24 gene,
  • Pnlip,
  • 1810007A24Rik,
  • pancreatic lipase
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