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Publication : BRAF: a driver of the serrated pathway in colon cancer.

First Author  Rustgi AK Year  2013
Journal  Cancer Cell Volume  24
Issue  1 Pages  1-2
PubMed ID  23845435 Mgi Jnum  J:199225
Mgi Id  MGI:5501347 Doi  10.1016/j.ccr.2013.06.008
Citation  Rustgi AK (2013) BRAF: A Driver of the Serrated Pathway in Colon Cancer. Cancer Cell 24(1):1-2
abstractText  In this issue of Cancer Cell, Rad and colleagues report findings that underscore the importance of oncogenic BRAF mutation coupled with microsatellite instability, p16Ink4a inactivation, and p53 mutation in the serrated pathway of colon cancer development. These findings provide translational insights into potential therapeutic intervention for BRAF mutant colon cancers.
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