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Protein Coding Gene : Pdxp pyridoxal (pyridoxine, vitamin B6) phosphatase

Primary Identifier  MGI:1919282 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  57028
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables magnesium ion binding activity; protein homodimerization activity; and pyridoxal phosphatase activity. Involved in pyridoxal phosphate catabolic process and regulation of modification of postsynaptic structure. Located in cell-cell junction. Is active in glutamatergic synapse and postsynapse. Is expressed in alimentary system; eye; limb; nervous system; and tail. Orthologous to human PDXP (pyridoxal phosphatase).
PHENOTYPE: Mice homozygous for a null allele exhibit increased GABA levels, improved spatial learning and memory, mild anxiety, weakness, and abnormal amino acid metabolism in the brain. [provided by MGI curators]
  • synonyms:
  • Pdxp,
  • hypothetical protein, MNCb-4193,
  • chronophilin,
  • AB041662,
  • pyridoxal (pyridoxine, vitamin B6) phosphatase,
  • 1600027H05Rik,
  • Chronophin,
  • PLP-phosophatase,
  • MGI:1930786

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Genome

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3 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

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Canonical gene --> Transcripts in specific strains.

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