| Primary Identifier | MGI:1918976 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 71726 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable DNA N-glycosylase activity; identical protein binding activity; and single-stranded DNA binding activity. Predicted to be involved in base-excision repair. Predicted to act upstream of or within DNA damage response. Predicted to be located in cytosol; fibrillar center; and nucleoplasm. Is expressed in several structures, including lower urogenital tract; palatal shelf; reproductive system; retina layer; and urethra epithelium. Orthologous to human SMUG1 (single-strand-selective monofunctional uracil-DNA glycosylase 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired base-excision repair and decreased cellular sensitivity to 5-hydroxymethyluridine toxicity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
