Primary Identifier | MGI:3045306 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 241624 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable 3'-5' exonuclease activity and RNA binding activity. Involved in piRNA processing. Part of PET complex. Is expressed in testis. Orthologous to human EXD1 (exonuclease 3'-5' domain containing 1). PHENOTYPE: Mice homozygous for a knock-out allele are fertile and viable, but exhibit defective biogenesis of antisense piRNAs and activation of transposons in male germ cells. [provided by MGI curators] |