Primary Identifier | MGI:3038749 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Fbxw7 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 5 and 6, which encode the F-box, were deleted via cre mediated recombination of loxP sites inserted in introns 4 and 6. An frt-flanked neo cassette remained in intron 4 after the excision of the floxed fragment. |