| Primary Identifier | MGI:95822 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 14813 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables NMDA glutamate receptor activity; monoatomic cation channel activity; and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Acts upstream of or within several processes, including excitatory postsynaptic potential; neuromuscular process controlling balance; and protein localization to postsynaptic membrane. Part of NMDA selective glutamate receptor complex. Is active in glutamatergic synapse and postsynaptic density membrane. Is expressed in several structures, including brain; colon; eye; gallbladder; and genitourinary system. Orthologous to human GRIN2C (glutamate ionotropic receptor NMDA type subunit 2C). PHENOTYPE: Homozygotes for targeted null mutations exhibit deficits in motor coordination and reduced granule cell responses to N-methy-D-aspartate in brain slices. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
