| Primary Identifier | MGI:1918464 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 68606 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable calmodulin-dependent protein phosphatase activity and protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in several processes, including negative regulation of cell-cell adhesion mediated by cadherin; positive regulation of cellular component biogenesis; and regulation of gene expression. Predicted to act upstream of or within apoptotic process. Predicted to be located in perinuclear region of cytoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and respiratory system. Orthologous to human PPM1F (protein phosphatase, Mg2+/Mn2+ dependent 1F). PHENOTYPE: Mice homozygous for a targeted mutation are not detected at weaning. Mice heterozygous for a targeted mutation display hyperactivity and an increase in pain threshold. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
