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Allele : Il6<tm1Mur> interleukin 6; targeted mutation 1, Richard Murray

Primary Identifier  MGI:2182222 Allele Type  Targeted
Attribute String  Null/knockout Gene  Il6
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced approximately 95% of exon 4. ELISA, both in vitro of thymic stromal cell supernatants stimulated by LPS and in vivo of sera from LPS stimulated animals, showed a lack of encoded protein in homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

15 Publication categories

Trail: Allele