Primary Identifier | MGI:2182222 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Il6 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin selection cassette replaced approximately 95% of exon 4. ELISA, both in vitro of thymic stromal cell supernatants stimulated by LPS and in vivo of sera from LPS stimulated animals, showed a lack of encoded protein in homozygous mutant mice. |