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Allele : Tg(Gata1*V205G)1Mym transgene insertion 1, Masayuki Yamamoto

Primary Identifier  MGI:5295641 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Gata1*V205G)1Mym
Strain of Origin  (C57BL/6 x DBA/2)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene consists of the murine Gata1 cDNA with a V205G (GTG to GGG) mutation under the control of the Gata1 genomic locus spanning 3.9 kb 5' of the hematopoietic IE exon to the second exon (GATA-1 HRD) which recapitulates endogenous Gata1 gene expression. The valine 205 to glycine substitution has been shown to reduce Zfpm1 (Fog-1) association. Five lines were made. This line is a high-expressing line.
  • mutations:
  • Insertion
  • synonyms:
  • V205G,
  • V205G
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele