| Primary Identifier | MGI:3808877 | Allele Type | Chemically induced (ENU) |
| Gene | Ikbkg | Inheritance Mode | Other (see notes) |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false | Project Collection | Beutler Mutagenetix |
| description | The phenotype associated with this allele is transmitted in an X-linked semidominant manner. |
| molecularNote | This mutation was identified in a toll-like receptor (TLR) signaling screen of G3 progeny of an ENU mutagenized male mouse. It comprises a T to C transition at nucleotide position 473, in the fourth of ten total exons, that results in replacement of a highly conserved leucine by proline at amino acid position 153 of the protein (L153P; variant 1, Genbank: NM_178590), in the first coiled-coil (CC1) domain. |
