| Primary Identifier | MGI:1915472 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 227613 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable GTP binding activity and double-stranded RNA binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Located in myelin sheath. Is expressed in brain ependyma; epithelial layer of oviduct; germ cell of testis; nasal epithelium; and respiratory system epithelium. Human ortholog(s) of this gene implicated in Leber congenital amaurosis with early-onset deafness. Orthologous to human TUBB4B (tubulin beta 4B class IVb). PHENOTYPE: Mice homozygous for a null allele display partial postnatal lethality and severe truncation of cilia on multi-ciliated cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
