Primary Identifier | MGI:5518827 | Allele Type | Targeted |
Gene | Ilk | Transmission | Germline |
Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Valine codon 386 (GTG) and threonine codon 387 (ACA) in exon 12 were changed to glycine (GGC) (p.V386G, p.T387G or p.V386_T387delinsGG) and a loxP site flanked neomycin resistance gene cassette was inserted into the 3' UTR in exon 13. The neo cassette was removed through subsequent Cre-mediated recombination. |