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Publication : Characteristics and biological functions of TRAF6.

First Author  Inoue J Year  2007
Journal  Adv Exp Med Biol Volume  597
Pages  72-9 PubMed ID  17633018
Mgi Jnum  J:159274 Mgi Id  MGI:4442152
Doi  10.1007/978-0-387-70630-6_6 Citation  Inoue J, et al. (2007) Characteristics and biological functions of TRAF6. Adv Exp Med Biol 597:72-9
abstractText  TRAF6 is divergent from other members of the TRAF family. Therefore, TRAF6 was expected to play physiological roles distinct from those of other TRAFs. In this chapter, we focused on the physiological functions specific to TRAF6 but not other TRAFs in immune system, formation of skin appendices, and nervous system development by describing abnormal phenotypes observed in TRAF6-deficient mice. The role of TRAF6 in osteoclastogenesis and the molecular mechanisms ofTRAF6-mediated signal transduction are described in other chapters.
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