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Publication : Cloning and characterization of pentylenetetrazol-related cDNA, PTZ-17.

First Author  Kajiwara K Year  1995
Journal  Brain Res Volume  671
Issue  1 Pages  170-4
PubMed ID  7537161 Mgi Jnum  J:22997
Mgi Id  MGI:70865 Doi  10.1016/0006-8993(94)01308-5
Citation  Kajiwara K, et al. (1995) Cloning and characterization of pentylenetetrazol-related cDNA, PTZ-17. Brain Res 671(1):170-4
abstractText  cDNAs related to pentylenetetrazol-induced bursting activity in neurons were screened by a differential hybridization method using normal and pentylenetetrazol-treated primary cultured neurons from the cerebral cortex of mice. Twenty clones of candidate cDNA with expression increased or decreased by treatment with pentylenetetrazol were obtained. One of them, PTZ-17, was sequenced. Injection of PTZ-17 derived RNA into Xenopus oocytes showed a large calcium inward current with extracellular application of pentylenetetrazol.
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