| Primary Identifier | MGI:2183221 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Gfap |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The insertion of a neomycin selection cassette deleted 2.0kb of the upstream regulatory region as well as sequence in exon 1 encoding the first 71 amino acids. Northern blot analysis of total brain RNA showed a lack of transcript produced from this allele. Encoded protein was undetected in homozygous mutant mice via immunohistochemical staining of astrocytes. |
