| Type | MGI:General | Description | after in vivo administration of tracer dipeptides (i.e. the fluorophore-conjugated dipeptide d-Ala-Lys-AMCA and the radiolabeled dipeptide d-[3H]Phe-Ala), homozygotes show a severe reduction in the accumulation of hydrolysis-resistant dipeptides in the kidney, indicating impaired tubule reabsorption of peptide-bound amino acids |
